Impairment of diastolic function during short-term anthracycline chemotherapy.
نویسندگان
چکیده
منابع مشابه
Impairment of diastolic function during short-term anthracycline chemotherapy.
OBJECTIVE To assess the early changes in left ventricular diastolic and systolic function due to anthracycline treatment. DESIGN A prospective study of cardiac function by radionuclide angiography in adults before and one month after the end of anthracycline treatment. PATIENTS 60 patients without cardiac disease treated with chemotherapy containing anthracycline. METHODS Cardiac function...
متن کاملLeft ventricular diastolic function after anthracycline chemotherapy in childhood: relation with systolic function, symptoms, and pathophysiology.
OBJECTIVES To examine left ventricular (LV) diastolic function in patients previously treated with anthracycline drugs for childhood malignancy. To consider clinical relevance, relations with systolic dysfunction, and the pathophysiology of anthracycline cardiotoxicity. DESIGN Cross sectional echocardiographic study of LV function. SETTING Supraregional centre for paediatric cardiology, pri...
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AIMS The benefits from anthracycline chemotherapy are undermined by potentially life-threatening cardiotoxicity. Transthoracic echocardiography is the most commonly used method for monitoring cardiotoxicity, and centres on the measurement of left ventricular systolic function. The aim of this study was to utilize two-dimensional speckle tracking echocardiography (2DSTE) at baseline and immediat...
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BACKGROUND Anthracycline affects various cell lines, which may contribute to left ventricular (LV) dysfunction and vascular remodelling. AIM To assess the complex influence of anthracycline chemotherapy on the echocardiographic parameters of LV systolic and diastolic function and indices of vascular function and structure. METHODS 35 women (age 50 ± 9 years old) with breast cancer scheduled...
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Anticancer treatments for childhood acute lymphoblastic leukaemia (ALL) are highly effective but are now implicated in causing impaired muscle function in long-term survivors. However, no comprehensive assessment of skeletal muscle mitochondrial functions in long-term survivors has been performed and the presence of persistent chemotherapy-induced skeletal muscle mitochondrial dysfunction remai...
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ژورنال
عنوان ژورنال: Heart
سال: 1995
ISSN: 1355-6037
DOI: 10.1136/hrt.73.1.61